Indexing Cerebrovascular Health Using Transcranial Doppler Ultrasound

Abstract Transcranial Doppler (TCD) blood flow velocity has been extensively used in biomedical research as it provides a cost-effective and relatively simple approach to assess changes cerebral dynamics track cerebrovascular health status. In this article we introduce new TCD-based timing index, TITCD, an indicator of vascular stiffening health. We investigate the correlations index existing indices, namely pulsatility augmentation with age, cardiorespiratory fitness (CRF) magnetic resonance imaging (MRI) (PIMRI). Notably, showed stronger CRF (r = −0.79) PIMRI 0.53) compared −0.65 no significant correlation PIMRI) (no or PIMRI), similar age index. The clearer relationship proposed aging factors underlines its utility early stiffening.